<!DOCTYPE html>
<html>

<head>
<script>

function boom()
{
  var frame = document.getElementById("f");
  var frameWin = frame.contentWindow;
  frame.parentNode.removeChild(frame);
  frameWin.onmouseover = function(){};
}

</script>
</head>

<body onload="boom();">
<iframe id="f" src="data:text/html,1"></iframe>
</body>

</html>